在乳房切除术后接受放射治疗的妇女中,乳房下部和乳房前部组织扩展器放置后的并发症
Seamus Caragher1, Alisha Paranzino2, Stephen Stearns1
1From the Division of Plastic Surgery, Brigham and Women's Hospital, Boston, MA.
Plastic and reconstructive surgery. Global open
|June 24, 2025
概括
胸前组织扩展器在乳房切除和放射后的乳房重建中是安全的. 无细胞皮肤基质可以防止并发症,而老年和化疗会增加风险.
科学领域:
- 整形外科 整形外科 整形外科
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
背景情况:
- 组织扩展器对于乳房重建至关重要,特别是在放射治疗后.
- 组织扩展器的胸前放置变得越来越受欢迎.
- 扩展器放置平面对放射治疗结果的影响需要进一步调查.
研究的目的:
- 评估前胸前与胸下组织扩展器在经过乳房切除术后放射治疗的患者中的安全性和结果.
- 为了确定组织扩展器放置后接受辐射的患者并发症的危险因素.
主要方法:
- 对接受乳房切除术,组织扩展器安置和放射治疗的患者 (2019-2021) 的回顾性审查.
- 收集临床,瘤,手术和辐射治疗的变量.
- 多变量分析以评估并发症率和风险因素.
主要成果:
- 胸前和胸下扩展器组之间的术后或辐射并发症率没有显著差异 (17%与18%).
- 无细胞皮肤矩阵的使用与明显较低的外科手术后并发症率相关 (OR:0.15;95% CI:0.03-0.78).
- 年龄增加 (OR:2.6;95% CI:1.02-6.63) 和新辅助化疗 (OR:16.7;95% CI:1.55-180) 是辐射相关并发症的重要风险因素.
结论:
- 胸前组织扩展器的放置是需要乳房切除术后放射治疗的患者的安全选择.
- 无细胞皮肤基质是这种患者群体中对并发症的关键保护因素.
- 在接受放射治疗的患者中,外科医生可以对胸前扩展器的安全性感到放心.
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