设计,合成和评估基于莱的氧化物激素衍生物作为潜在的抗衰老剂,针对Keap1-Nrf2通路

Jie Wang1, Xuejing Peng1,2, Xinyue Zhang1

  • 1College of Pharmacy, Gansu University of Chinese Medicine, Lanzhou, People's Republic of China.

概括

一种新型的莱因衍生物,化合物4b,通过调节Keap1-Nrf2通路,显示出强大的抗氧化和抗衰老特性. 这种化合物显著增强了细胞和生物体的抗压能力,为治疗与年龄相关的疾病提供了前景.

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