ULK1,ATG13和FIP200的三元相互作用是ULK复合体形成和自的必要条件

Yutaro Hama1,2,3, Yuko Fujioka1, Hayashi Yamamoto3,4

  • 1Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan.

eLife
|June 24, 2025
PubMed
概括

在哺乳动物中,ULK1-ATG13-FIP200复合体对于启动自是必不可少的. 这项研究揭示了其组装的结构基础,这对自细胞形成和细胞调节至关重要.

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