相关实验视频
Updated: May 2, 2026

11:19
Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
11.6K
一项为期6年的随机对照试验,针对大牙患者的不同植入物设计
Stefan Matthijs1, Véronique Christiaens1, Carine Matthys2
1Department of Periodontology & Oral Implantology, Faculty of Medicine and Health Sciences, Dental School, Ghent University, Ghent, Belgium.
Clinical implant dentistry and related research
|June 24, 2025
概括
牙植入物部设计和支柱连接类型对长期的脊柱骨稳定性和上超额置的周围植入物健康影响很小. 这项研究证实了六年后的高生存率和稳定的骨水平.
科学领域:
- 牙科植入物学 牙科植入物学
- 牙周病学 牙周病学
- 生物材料科学 生物材料科学
背景情况:
- 牙植入物周围的骨重塑是一个令人担忧的问题.
- 建议使用微线程和平台移动连接来缓解骨损失.
- 使用可控变量的长期研究是有限的.
研究的目的:
- 评估植入物部设计 (微线程与非微线程) 和支柱连接类型 (内部形与外部平面到平面) 对骨重塑和周围植入物健康的长期影响.
- 报告经过至少六年的功能后,由四个植入物支的条形保持的尾过长的临床结果.
主要方法:
- 这是一项随机对照试验,涉及25名接受四种植入物支持的上置的患者.
- 每位患者都接受了四种不同的设计的植入物:内部连接/微线程 (IMT),内部连接/无微线程 (INMT),外部连接/微线程 (EMT) 和外部连接/无微线程 (ENMT).
- 骨损失 (CBL),斑块得分 (PS),探测出血 (BoP) 和探测口袋深度 (PPD) 在安置后的一年和六年被评估.
主要成果:
- 六年后,平均顶部骨损失为0.37毫米 (SD:0.61).
- 随着时间的推移,四种植入物设计之间没有发现CBL的统计学上显著差异.
- 在6年的随访期间,微线程和连接类型都没有显著影响CBL,PDD,BOP或PS.
结论:
- 支持四种植入物的尾过度合显示了高植入物和假肢存活率,在六年后具有稳定的脊骨.
- 微线程的存在和植入物 - 支架连接的类型对周围植入物骨损失的影响有限.
- 周植入体健康指标表明,研究队列中没有周植入体炎.
更多相关视频
相关概念视频
Blind Procedures
10.8K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.8K
Crossover Experiments
3.4K
Crossover experiments, also called the repeated-measurements design, is a study design in which all experimental units are exposed to all treatments in different periods. Crossover experiments are generally used in psychology, the pharmaceutical industry, agriculture, and medicine.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
Crossover designs are performed even with smaller sample sizes since the samples can act as their controls. These are better than simple randomized trials since patients are exposed to all the treatments.
3.4K
Bioavailability Study Design: Healthy Subjects Versus Patients
248
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
248
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
407
Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to subjects...
407
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs
419
Bioequivalence experimental study designs play a pivotal role in testing the effectiveness of various treatments. Key among these are the repeated measures, cross-over, carry-over, and Latin square designs. In the repeated measures design, each subject receives all treatments, allowing for temporal comparisons. This type of design is useful in reducing variability but requires careful planning to avoid bias.The cross-over design, an economical method, involves sequential administration of...
419

