Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Genetic variation in antidiabetic drug targets: associations with Parkinson's disease risk and age at onset.

NPJ Parkinson's disease·2026
Same author

Long-Term Risk of Parkinson's Disease Following Irritable Bowel Syndrome: A Nationwide Population-Based Cohort Study.

Healthcare (Basel, Switzerland)·2026
Same author

Incidence of anxiety disorders following Parkinson's disease: a population-based cohort study.

Frontiers in psychiatry·2026
Same author

Post-gadolinium T1 alterations in Parkinson's disease and essential tremor.

NPJ Parkinson's disease·2026
Same author

Development of AI-based dopamine transporter (DAT) image generation technique using early phase [18F]-FP-CIT PET imaging.

PloS one·2026
Same author

Hypofractionated Gamma Knife Radiosurgery for Large Brain Metastases in Surgery-Ineligible Patients: Outcomes of a Uniform 5-Fraction Regimen.

Cancers·2026

相关实验视频

Updated: Sep 18, 2025

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.1K

在分阶段双边深度大脑刺激手术治疗帕金森病期间的连续大脑转移模式.

Junhyung Kim1, Sungyang Jo2, Sun Ju Chung2

  • 1Department of Neurological Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Operative neurosurgery (Hagerstown, Md.)
|June 24, 2025
PubMed
概括

在帕金森病的深度大脑刺激 (DBS) 手术期间的大脑转移是显著的,特别是在内球体内. 一个分阶段的手术方法有助于最大限度地减少准错误,允许程序之间的调整.

关键词:
大脑的转移大脑的转移深度大脑刺激是什么?基于框架的立体影像.星球的内部内部.亚体体内核的细胞核

更多相关视频

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

22.6K
A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test
07:14

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

Published on: May 31, 2016

14.9K

相关实验视频

Last Updated: Sep 18, 2025

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

13.1K
Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
11:12

Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation

Published on: July 16, 2014

22.6K
A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test
07:14

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

Published on: May 31, 2016

14.9K

科学领域:

  • 神经外科 神经外科
  • 医疗成像医学成像
  • 神经学 神经学

背景情况:

  • 大脑转移,大脑结构的移位,导致立体神经外科手术的准不准确.
  • 深度大脑刺激 (DBS) 是帕金森病的关键治疗方法,但大脑转移可能会使双边程序复杂化.

研究的目的:

  • 为了研究在帕金森病中分阶段双边DBS手术期间的连续大脑转移模式.
  • 评估大脑转移对GPi和STN的目标准确性的临床影响.
  • 评估分阶段双边准策略在缓解大脑转移方面的有效性.

主要方法:

  • 在105名帕金森病患者中进行了210次DBS手术的定量图像分析.
  • 在分阶段的双边DBS期间,通过GPi和STN在四次MRI会议的坐标位移来测量大脑转移.
  • 转移在三个配置中进行了评估:第一个DBS后,第二次DBS前与第二次DBS后,以及第一次DBS前与第二次DBS后.

主要成果:

  • 大脑转移主要发生在后部,下部和中部方向,GPi的幅度大于STN.
  • 临床相关的大脑转移 (>3毫米) 在第一个DBS后观察到6.8%的GPi,在第二个DBS后观察到高达20.3%的GPi和4.1%的STN.
  • 在第二次手术中,相对于重新扫描的MRI,大脑转移减少了 (4.1% GPi,0% STN),支持分阶段准. 肺脑病和低血压与增加的大脑转移相关.

结论:

  • 大脑转移是对帕金森病双边DBS手术的关键因素.
  • 分阶段的双边DBS程序为准确的准提供了优势,特别是对于GPi.
  • 这一策略有助于最大限度地减少准错误,改善手术结果.