中国老年人多病症负担与抑郁症状之间的关系:一项前性10年队列研究
Hong-Guang Zhang1, Jia-Feng Wang1, Anfeirea Jialin1
1Affiliated Mental Health Center & Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.
Journal of affective disorders
|June 24, 2025
概括
多病症的数量和具体模式显著增加了老年人抑郁症状 (DS) 的风险. 患有消化/关节炎或呼吸系统疾病的个人需要更密切的心理健康监测.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 多病症,即多种慢性疾病的同时发生,越来越被认为是老龄化人口的重大健康问题.
- 共同的潜在机制和风险因素有助于多病症集群,影响抑郁症状 (DS) 的发展.
- 现有研究强调,需要了解慢性疾病的数量和特定组合如何影响老年人的心理健康.
研究的目的:
- 调查60岁及以上个体慢性疾病数量与抑郁症状发展之间的关联.
- 通过隐性类分析 (LCA) 识别多病症的不同模式.
- 检查特定多病症模式与发展抑郁症状的风险之间的关系.
主要方法:
- 在2011年6月至2020年9月的中国健康与退休长度研究 (CHARLS) 中,对1988名60岁以上的参与者进行了长度研究.
- 通过自我报告对12种慢性疾病进行评估,并使用10项流行病学研究中心抑郁症量表 (CESD-10) 评估抑郁症症状.
- 应用隐性类分析 (LCA) 来识别多病态模式和考克斯比例危险回归模型来分析与DS风险的关联.
主要成果:
- 在随访期间,发现了986例抑郁症状.
- 高血压,中风,消化系统疾病,关节炎,慢性肺部疾病和脏疾病与增加DS风险有显著的关联.
- 每个额外的慢性疾病都会使DS的危险增加13%. 确定了四种多病态模式,其中消化/关节炎和呼吸模式显示出明显更高的DS风险.
结论:
- 多病症的计数和特定模式都与老年人抑郁症状风险增加有显著联系.
- 经历复杂健康状况的老年人,特别是那些有消化/关节炎和呼吸系统多病症的老年人,需要加强心理健康监测.
- 这些发现强调了综合护理方法对于管理多病症和预防老年人抑郁症状的重要性.
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