相关实验视频
Updated: Sep 18, 2025

07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
8.5K
婴儿饮食建议减少IgE介导的蛋,花生和牛奶过敏
Summer V M Walker1, Nina D'Vaz2, Rachelle A Pretorius3
1The Kids Research Institute Australia, the University of Western Australia, Nedlands, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
概括
提供最新的婴儿养指南导致更早的过敏原引入,显著降低了花生,蛋和牛奶过敏的风险.
科学领域:
- 儿科过敏和免疫学
- 公共卫生干预 公共卫生干预
- 婴儿营养 婴儿营养
背景情况:
- 以前的婴儿养指南建议推迟常见过敏原的引入.
- 最近的证据支持早期引入像花生和蛋这样的过敏原来降低过敏风险.
- 婴儿养建议已经转向了早期的过敏原暴露.
研究的目的:
- 为了比较1岁的IgE介导食物过敏的发病率.
- 评估更新的婴儿养指南对过敏患病率的影响.
- 在指南变更之前和之后评估过敏风险.
主要方法:
- 研究了两组具有过敏家族史的婴儿.
- 第1组没有收到具体的食建议;第2组在6个月后收到更新的指南.
- 食物过敏原敏感性和IgE介导过敏症在1岁时被评估.
主要成果:
- 早期引入花生,蛋和牛奶的情况在第2组中被观察到.
- 结合IgE介导过敏的联合患病率在第2队列 (4.1%) 与第1队列 (12.6%) 相比显著较低.
- 对于花生 (1.1%对5.8%),蛋 (2.8%对11.7%) 和牛奶 (0.5%对2.4%) 的过敏症,特别减少.
结论:
- 直接向家庭提供最新的食物过敏预防指南是有效的.
- 这种干预措施有助于婴儿更早地引入过敏原.
- 早期引入可显著降低IgE介导的花生,蛋和牛奶过敏的患病率.
相关概念视频
Development of Immunocompetence
462
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
462
Allergic Reactions
29.0K
Overview
29.0K
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
430
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
430
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
484
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
484
Antibody Structure
61.4K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
61.4K
Allergic Drug Reactions
1.0K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.0K

