太极拳作为一种心身运动,在冠状动脉疾病中调节内皮功能:一项随机临床试验
Yameng Li1, Cuihan Li2, Jiansheng Wen3
1Department of Physical Education, Northwestern Polytechnical University, Xi'an, China; College of Physical Education and Sports, Beijing Normal University, Beijing, China.
Complementary therapies in medicine
|June 24, 2025
概括
太极拳 (TC) 和有氧运动 (AE) 都改善了冠状动脉疾病 (CAD) 患者的内皮功能. TC显示了与AE相比的好处,即使在HDL水平没有显著变化.
科学领域:
- 心血管研究研究心血管研究
- 运动生理学 运动生理学
- 综合医学是一个整体的医学.
背景情况:
- 内皮功能障碍是冠状动脉疾病 (CAD) 的关键指标.
- 像太极拳 (TC) 这样的心身炼被探索为CAD的治疗选择.
- 在CAD患者中,TC与有氧运动 (AE) 对内皮功能的比较影响尚未得到充分证实.
研究的目的:
- 为了比较12周的太极拳 (TC) 与有氧运动 (AE) 对冠状动脉疾病 (CAD) 患者内皮功能的影响.
- 在TC和AE干预后评估内皮功能生物标志物和脂质配置文件的变化.
主要方法:
- 一个并行组,评估者盲目的随机临床试验 (RCT),涉及48名CAD患者.
- 参与者被分配到一个监督的12周的太极拳 (TC) 或有氧运动 (AE) 计划中,每周训练三次.
- 使用氧化 (NO),内甲蛋白 (ET),VCAM-1和ICAM-1来评估内皮功能;也测量了脂质配置文件 (HDL,TC,TG,LDL).
主要成果:
- TC和AE组都显示了内皮功能的显著改善,NO增加和ET,VCAM-1和ICAM-1水平降低 (P<0.05).
- 高密度脂蛋白 (HDL) 水平在AE组显著增加,但在TC组没有 (P<0.05).
- 在任何组中都没有观察到总胆固醇 (TC),甘油三 (TG) 或低密度脂蛋白 (LDL) 的显著变化 (P>0.05).
结论:
- 太极拳 (TC) 是一种可行的心身运动,可以改善冠状动脉疾病 (CAD) 患者的内皮功能,与有氧运动 (AE) 相似.
- 即使血清脂质水平保持不变,TC也提供心血管益处.
- 这项研究强调TC作为一种潜在有效的替代或辅助疗法,用于在CAD中管理内皮功能.
相关概念视频
01:26Atherosclerosis III: Management
42
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
42
01:26Coronary Artery Disease IV: Preventive Measures
39
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
39
01:26Coronary Artery Disease II: Pathophysiology
42
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
42
01:30Coronary Artery Disease III: Clinical Manifestations
38
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
38
01:20Exercise and Cardiovascular Response
1.1K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
1.1K
01:30Coronary Artery Disease I: Introduction
69
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
69