精神病,神经发育和神经学障碍中的左右混:系统性审查
Moritz Thaler1, Sebastian Ocklenburg2
1Department of Psychology, MSH Medical School Hamburg, Hamburg, Germany; ISPP Institute for Safety of Patients and Health Professionals MSH Medical School Hamburg, Hamburg, Germany.
Brain research bulletin
|June 24, 2025
概括
左右混在某些神经和精神疾病中更为普遍. 这一系统性审查强调了阿尔茨海默病和发育地形失调 (DTD) 的损害.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 神经学 神经学
背景情况:
- 左右混是常见的,但在特定疾病中升高.
- 了解患病率变化对于诊断和治疗至关重要.
- 现有的研究表明,与神经和发育条件有联系.
研究的目的:
- 系统地审查那些有较高左右混患病率的疾病.
- 识别与空间导向缺陷相关的神经和发育状况.
- 综合当前关于临床群体中左右混的证据.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在谷歌学者,PubMed和Mendeley进行的搜索.
- 包括20个定量案例控制研究.
主要成果:
- 围叶病变和与阿尔茨海默病相关的损伤会损害左右方向.
- 发育地形偏向失调 (DTD) 显示了方向分配中的发育障碍.
- DTD与海马-右前额叶皮层连接性降低和方向歧视较差有关.
结论:
- 特定的大脑病变和疾病,如阿尔茨海默氏症和DTD,与严重的左右混有关.
- 需要进一步的研究来定义和运行临床环境中的左右混.
- 准确的临床评估需要标准化的定义和评估.
更多相关视频
相关概念视频
Lateralization
523
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
523
Disorders of the Nervous Tissue
1.7K
Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
1.7K
Language and Cognition
460
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
460
Cerebral Hemispheres
571
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
571
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders
1.0K
Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
1.0K
Biological Causes of Schizophrenia
156
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
156


