新生儿在输入高块葡萄糖后出现右心房血栓:一个病例系列
Prakash Duraisamy1, Anand Nandakumar1, Harikrishnan Kelamangalam NeelakantaKurup2
1Department of Neonatology, Government Medical College, Thiruvananthapuram, India.
Journal of neonatal-perinatal medicine
|June 24, 2025
概括
通过管静脉导管输注高度的葡萄糖可能会导致新生儿的心脏血栓. 这种情况是危及生命的,强调了早期检测和干预的必要性,以改善结果.
科学领域:
- 新生儿医学 新生儿医学
- 心血管病理学心血管病理学
- 儿科重症监护 儿科重症监护
背景情况:
- 新生儿心脏血栓是一种罕见但严重的疾病,患病率和死亡率很高.
- 危险因素包括侵袭性手术,代谢问题,以及重症婴儿的超流体.
- 右心房血栓在新生儿中尤其令人担忧.
研究的目的:
- 调查新生儿右心房血栓的临床特征,风险因素和结果.
- 通过管静脉导管强调高度葡萄糖输注的潜在作用.
主要方法:
- 五个新生儿的回顾案例系列.
- 在2022年1月至2024年12月期间收集的数据.
- 经过心声扫描证实了诊断,这是由于无法解释的心率下降.
主要成果:
- 所有五名新生儿都通过带静脉导管接受了高度葡萄糖输液,用于在血栓发育之前的高胰岛素低血糖症.
- 心声扫描在所有病例中都显示出右心房血栓.
- 三名新生儿在抗凝药治疗中幸存下来;两名因并发症而死亡.
结论:
- 新生儿的大型心脏血栓带有由于栓塞和败血症的高死亡风险.
- 通过管静脉导管输入高度葡萄糖被确定为潜在的危险因素.
- 早期检测和干预,如抗凝血和血栓溶解,对于改善生存率至关重要.
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