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Updated: Sep 18, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Published on: October 26, 2015

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对循环林依赖性激酶8 (CDK8) 抑制剂作为抗癌剂的全面描述

Ying Liu1, Luhan Sun1, Hongyuan Lu2

  • 1Department of China Medical University-The Queen's University of Belfast Joint College, China Medical University, Shenyang, PR China.

Bioorganic & medicinal chemistry
|June 24, 2025
PubMed
概括

循环素依赖性激酶8 (CDK8) 是癌症治疗的有希望的标. 本综述详细介绍了选择性CDK8抑制剂,它们的结构和结构-活性关系,以指导未来的药物开发.

关键词:
这是一种CDK8抑制剂.癌症 癌症 癌症 癌症药理学活动 药理学活动结构修改是指结构的修改.结构与活动关系 (SAR)

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