相关实验视频

Updated: Sep 18, 2025

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
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Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

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NOVA1/2基因和神经发育中的替代拼接

Amélie Piton1

  • 1Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U964, Illkirch, France; Université de Strasbourg, 67 400 Illkirch, France; Genetic diagnosis laboratory, Strasbourg University Hospital, 67 090 Strasbourg, France.

Current opinion in genetics & development
|June 24, 2025
PubMed
概括

NOVA1和NOVA2RNA结合蛋白对大脑发育至关重要,通过替代拼接控制基因表达多样性. NOVA2中的突变会导致严重的神经发育障碍,这突显了它们在神经健康中的重要性.

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