由Streptococcus anginosus引起的中枢神经系统疾病的谱群:一个单中心病例系列
Jennifer Meylor1, Raquel Farias-Moeller2, Niyati Mehta2
1Department of Neurology, Division of Pediatric Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Pediatric neurology
|June 24, 2025
概括
儿童中枢神经系统感染的Streptococcus anginosus群 (SAG) 经常出现急性症状和内. 虽然预后通常有利,但一些儿童在PICU入院后会出现神经和心理缺陷.
科学领域:
- 儿科神经学 儿科神经学
- 传染性疾病 传染性疾病
- 神经生理学 神经生理学
背景情况:
- 儿童中枢神经系统 (CNS) 感染可能导致显著的发病率.
- 性菌群 (SAG) 是一种新兴的病原体,导致中枢神经系统感染.
研究的目的:
- 描述由SAG引起的儿科中枢神经系统感染的电生理学和神经学结果.
- 了解儿童SAG中枢神经系统感染的临床表现和后果.
主要方法:
- 回顾15名儿科患者的病例系列,他们被送往儿科重症监护室 (PICU).
- 对临床数据,神经成像和脑电图 (EEG) 发现的分析.
- 神经学和神经心理评估在放药时.
主要成果:
- 大多数患者以前健康,急性发烧,头痛和疲劳.
- 最常见的中枢神经系统并发症 (93%) 是体下或体外.
- 47%的患者发生了发作,20%的患者经历了亚临床发作;33%的患者有剩余的神经缺陷,神经心理测试显示了情绪和认知方面的困难.
结论:
- 由于SAG引起的儿童中枢神经系统感染通常呈现非特异性症状和内.
- 虽然预后往往是有利的,但很大一部分儿童患有神经和心理缺陷.
- 持续的EEG监测和全面的神经心理评估对于管理这些患者至关重要.
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