儿童和护理人员参与开发儿科核心结果集:一个横截面分析
Ruobing Lei1,2, Janne Estill3,4, Haiyun Wang2,5
1Chevidence Lab of Child & Adolescent Health, Children's Hospital of Chongqing Medical University, Chongqing, China.
BMJ evidence-based medicine
|June 24, 2025
概括
超过一半的儿科核心结果集 (COS) 包括儿童和照顾者. 需要制定战略来改善儿童的包容性.
科学领域:
- 儿科研究方法的方法学.
- 患者和公众参与医疗保健研究.
背景情况:
- 核心结果集 (COS) 对于标准化临床试验结果至关重要.
- 确保儿童和护理人员在COS发展中的有意义参与,对于相关性和适用性至关重要.
研究的目的:
- 评估儿童和护理人员参与开发儿科核心成果集 (COS) 的程度和性质.
- 识别儿童和护理人员参与COS发展的促进者和障碍.
主要方法:
- 对儿科COS的系统审查,并通过对有效性试验中核心结果措施数据库的搜索来补充.
- 包括COS特征和参与方法的描述性和主题分析.
- 参与程度的两步评估:考虑结果列表的形成和整合在确定结果的重要性.
主要成果:
- 包括114个儿科COS;其中60个 (53%) 涉及儿童和护理人员.
- 在60个COS中,29个COS (48%) 的初始结果列表形成时考虑了儿童和照顾者的观点,通常是通过采访.
- 在60个COS中,有35个 (58%) 的结果在确定结果的重要性时完全纳入了观点,通常使用Delphi调查与共识会议;最年轻的参与者是7岁. 患者群体参与是关键的促进因素.
结论:
- 虽然近期超过一半的儿科COS发展涉及儿童和护理人员,但观察到不同程度的参与.
- 需要制定和实施具体策略,以加强和确保儿童和照顾者的强有力的参与未来的COS发展.
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