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相关概念视频

Infertility in Males01:23

Infertility in Males

339
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
339
Sperm Structure and Semen Composition01:22

Sperm Structure and Semen Composition

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During ejaculation, males release around 2-5 milliliters of semen, which is a complex mixture of mature sperm and various fluids produced by accessory glands. The mature sperm cells measure approximately 60 micrometers in length and consist of a head, neck, midpiece, and tail. The head is flattened and tapered, measuring about 4 to 5 micrometers in length. It contains a nucleus with condensed chromosomes and an acrosome, a cap-like structure filled with enzymes essential for penetrating the...
5.3K
Sperm Transport01:15

Sperm Transport

1.5K
The journey of sperm from its origin to the point of ejaculation begins within the seminiferous tubules of the testis. Here, Sertoli cells produce fluid that propels non-motile sperm through a series of conduits, starting with the straight tubules leading to the rete testis. This interconnected network of tubules acts as the initial pathway for sperm, guiding them into the efferent ductules and then into the epididymis for maturation.
The maturation phase occurs in the epididymis, where sperm...
1.5K
Spermatogenesis01:41

Spermatogenesis

103.5K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
103.5K
Testes: Histology01:27

Testes: Histology

1.6K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
1.6K
Accessory Glands of the Male Reproductive System01:16

Accessory Glands of the Male Reproductive System

2.1K
The accessory ducts involved in sperm maturation and transportation include the epididymides, vasa deferentia, ejaculatory ducts, and urethra. These ducts play a critical role in the maturation, storage, and transportation of sperm from the testes to the urethra, where it is then released during ejaculation.
The epididymis is a small, comma-shaped organ located at the back of each testicle. The epididymis can be divided into three main parts: the head, body, and tail. The head of the epididymis...
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相关实验视频

Updated: Sep 18, 2025

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
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精液粘度过高与精子质量和功能不佳有关.

Jiao Qin1,2, Qingyuan Cheng1,2, Yingbi Wu1,2

  • 1Department of Andrology/Sichuan Human Sperm Bank, West China Second University Hospital, Sichuan University, 1416 Chenglong Avenue, Jinjiang District, Chengdu, Sichuan, China.

Journal of assisted reproduction and genetics
|June 24, 2025
PubMed
概括

精液高粘度 (SHV) 显著降低精子质量,影响精子的运动性,活力和体功能. 这种情况在12.4%的样本中发现,需要对男性不孕不育的评估给予更大的临床关注.

关键词:
男人不孕不育的情况精液的超粘性 精液的超粘性精子的功能 精子的功能精子质量 精子质量

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U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index
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Collection of Post-mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice
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Collection of Post-mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice

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Last Updated: Sep 18, 2025

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03:28

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U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index
09:16

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296
Collection of Post-mating Semen from the Female Reproductive Tract and Measurement of Semen Liquefaction in Mice
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科学领域:

  • 安德罗学和生殖医学.
  • 精子生物生物学 精子生物
  • 男人不孕症研究研究

背景情况:

  • 精液粘度过高 (SHV) 是男性不孕症的一个新兴因素,可能会阻碍精子运动.
  • 对于SHV影响精子参数和整体功能的确切机制,需要进一步阐明.

研究的目的:

  • 为了确定SHV在大量男性人口中的流行率.
  • 调查SHV与各种精子质量参数之间的关联,包括DNA完整性,体功能,线粒体功能和精液等离子体组成.

主要方法:

  • 对55733个精液样本进行了追溯分析.
  • 评估SHV患病率及其与精子运动,形态,活力,DNA碎片化指数 (DFI),宏体功能,线粒体膜潜力和精子血成分 (果糖水平) 的相关性.

主要成果:

  • 在12.4%的样本中存在SHV,其患病率与精液量,精子数量,渐进性运动性,活力和正常形态的减少有关.
  • 在SHV样本中,表现出大粒体功能受损和较低的线粒体膜潜力.
  • 轻度/中度的SHV显示较低的DFI,而严重的SHV显示增加了高DNA稳定性 (HDS) 和染色质凝聚异常. 在SHV组中发现了异常的果糖水平.

结论:

  • SHV对精子功能产生多方面的负面影响,不仅仅是精子的运动能力,对男性生育能力的评估具有重要的临床意义.
  • 临床医生应该更多地关注精液粘度评估.
  • 标准化粘度测试和针对相关腺功能障碍的向治疗是必要的,以提高诊断精度和治疗疗效.