超越炎症性肠病:蛋白作为三虫病的标记物? 一个案例报告
1Department of Pediatrics, Faculty of Medicine, Umm Al Qura University, Makkah, Saudi Arabia.
Case reports in gastroenterology
|June 25, 2025
概括
本案例报告突出了一个罕见的儿童便calprotectin升高的例子,这最终归因于trichobezoar,胃肠道中的毛球.
科学领域:
- 胃肠病学 胃肠病学
- 儿科医学 儿科医学
- 诊断生物标志物 诊断生物标志物
背景情况:
- 三动物是毛发聚集,引起胃肠道 (GI) 症状.
- 便calprotectin (FC) 是一种肠道炎症生物标志物,通常在炎症性肠病 (IBD) 中升高.
- 升高的FC通常与三动物无关.
研究的目的:
- 报告一个与三动物相关的高FC的儿科病例.
- 讨论在异常的胃肠道条件下FC的诊断和临床影响.
主要方法:
- 一个患有慢性腹痛的7岁女孩接受了诊断工作.
- 测量了便中的calprotectin水平,显示出明显的升高.
- 上部和下部内镜检查发现了三动物 (拉泽综合征).
- 进行了内镜和手术干预.
主要成果:
- 在没有IBD的情况下观察到便calprotectin (433.9 mg/kg) 的升高.
- 诊断出一个从胃延伸到十二指肠的大型trichobezoar.
- 组织学显示轻微的反应性胃,没有显著的胃肠道炎症的迹象.
结论:
- 这一案例表明,trichobezoars可以是高便calprotectin的未被识别的原因.
- 临床背景对于解释FC水平至关重要,特别是在儿科胃肠道病例中.
- 在非IBDGI病理中对FC的进一步调查可能是有必要的.
更多相关视频
相关概念视频
Inflammatory Bowel Disease II: Crohn's Disease
401
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
401
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
430
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
430
Inflammatory Bowel Disease I: Ulcerative Colitis
345
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
345
Chronic Bowel Disorders: Introduction
543
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
543
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
256
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
256
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
209
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
209


