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早期青春期DLK1和MKRN3基因的甲基化指数

E A Sazhenova1, O Yu Vasilyeva1, D A Fedotov1

  • 1Scientific Research Institute of Medical Genetics, Tomsk National Research Medical Center of the Russian Academy of Sciences, Tomsk, Russia.

Vavilovskii zhurnal genetiki i selektsii
|June 25, 2025
PubMed
概括

在MKRN3和DLK1基因的表观遗传变化,特别是DNA甲基化,与早期青春期 (PP) 有关. 这项研究发现PP女孩的甲基化模式发生变化,特别是在单独的上腺和中央PP病例中.

关键词:
在 DLK1 的位置上.在MKRN3For中使用.基因组印记是基因组的印记.发生性腺激素释放激素 (GnRH)下垂体 - 下垂体 - 淋巴腺轴 (HPG)过早的青春期 过早的青春期

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