在Fontan循环中的怀孕结果:系统性审查和元分析
Tanawat Attachaipanich1, Suthinee Attachaipanich2, Kotchakorn Kaewboot3
1Department of Internal Medicine, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA.
概括
怀孕的妇女在Fontan循环带来风险,包括心律失常和早产. 仔细的孕前咨询和多学科护理对于改善Fontan患者的孕产妇和新生儿结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 生殖医学 生殖医学
- 儿童心脏病学 儿童心脏病学
背景情况:
- 芬坦手术的生存率有所提高,增加了芬坦循环的成年女性的数量.
- 有限的数据存在于Fontan循环妇女的怀孕结果.
研究的目的:
- 系统地审查和综合有关Fontan循环妇女怀孕的孕妇和新生儿结果的数据.
主要方法:
- 在PubMed,Embase,Web of Science和Cochrane CENTRAL的系统文献搜索,截至2024年9月25日.
- 包括报告Fontan循环怀孕中母亲或新生儿结局的研究.
- 不包括案例系列和案例报告.
主要成果:
- 分析了包括400名妇女和1260个怀孕在内的18项研究.
- 孕产妇心律失常 (心上心律失常) 的综合发病率为6.59%,孕产妇心力衰竭为3.71%.
- 高频率的早产 (57.31%) 和新生儿死亡率 (4.38%) 主要是由于早产并发症.
结论:
- 患有Fontan循环的妇女的怀孕与不良的孕产妇和新生儿结局有关.
- 预孕咨询和多学科护理对于优化怀孕计划和结果至关重要.
- 密切监测和专业护理对于这种高风险的产科患者群体至关重要.
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