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根据NHANES数据库的数据,BMI对血清维生素D相关睡眠剥夺的调解作用
Boya Gong1,2, Bei Xu3, Chaoban Wang1,2
1Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.
Frontiers in nutrition
|June 25, 2025
概括
适当的维生素D水平显著降低睡眠不足的风险,无论是直接的还是通过管理肥胖 (体重指数). 维持足够的维生素D可能有助于减轻睡眠问题,特别是较低的BMI.
科学领域:
- 营养科学 营养科学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 睡眠不足是一个全球性的健康问题,对身体和心理健康有重大影响.
- 现有的研究将睡眠不足与维生素D和肥胖联系起来,但组合效应的研究不足.
- 这项研究解决了了解血清维生素D,肥胖和睡眠不足之间的相互作用的差距.
研究的目的:
- 研究身体质量指数 (BMI) 在血清维生素D水平与美国成年人睡眠不足之间的关联中的调解作用.
- 量化维生素D对睡眠不足风险的直接和间接影响,考虑到肥胖状况.
主要方法:
- 一项横截面研究利用了国家健康和营养检查调查 (NHANES) 数据库 (2007-2018,2021-2023) 中20,865名参与者的数据.
- 后勤回归分析以确定维生素D水平与睡眠剥夺之间的关系.
- 调解分析以评估BMI在维生素D与睡眠剥夺相关性中的作用.
主要成果:
- 增加的维生素D水平,特别是BMI低于第75百分位,与睡眠剥夺的风险显著降低有关 (OR=0.70).
- 血清维生素D在降低睡眠剥夺风险方面表现出显著的直接作用 (P < 0.001).
- 通过对BMI (P < 0.001) 的影响,观察到维生素D对睡眠剥夺风险的显著间接影响.
结论:
- 维生素D通过直接途径和间接地通过其对BMI的影响影响美国成年人的睡眠剥夺.
- 维生素D补充剂可能为睡眠不足的人提供潜在的治疗策略.
- 优化维生素D水平,特别是与保持健康的BMI一起,可以帮助减轻睡眠不足的风险.
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