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Updated: Sep 18, 2025

Zebrafish Model of Neuroblastoma Metastasis
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细胞外矩阵拓学驱动在神经母细胞瘤中上腺对介质细胞过渡的作用

Antonios Chronopoulos1, Chandra Kaladhar Vemula1, Vic Zamloot1

  • 1Cancer and Blood Disease Institute, Children's Hospital Los Angeles, 4650 Sunset Blvd, Los Angeles, California, 90027, USA.

Advanced materials (Deerfield Beach, Fla.)
|June 25, 2025
PubMed
概括

细胞外矩阵 (ECM) 地形驱动神经母细胞瘤 (NB) 细胞过渡到介质细胞 (MES) 身份,促进转移和治疗耐药性. 针对ECM地形可能为高风险的NB提供新的治疗策略.

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