关于腹膜间皮质瘤管理的共识指南
Leanne M Brown1, Sarah G Wilkins1, Varun V Bansal1
1Yale School of Medicine, New Haven, Connecticut, USA.
Cancer
|June 25, 2025
概括
这一共识提供了关于腹膜间皮瘤 (PeM) 管理的最新指导方针,强调多学科评估和多模式治疗. 进一步的研究对于改善这种罕见癌症的基于证据的治疗至关重要.
科学领域:
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 腹膜间皮瘤 (PeM) 由于罕见性,异质性和临床证据有限,因此存在重大治疗挑战.
- 现有的管理指南需要更新,以反映当前的理解和临床实践.
研究的目的:
- 更新2018年芝加哥共识指南,用于腹膜间皮瘤管理.
- 建立一个以共识驱动的途径来解决PeM治疗.
主要方法:
- 采用了经过修改的Delphi技术,在101名参与者中进行了两轮投票.
- 在各种管理途径块中评估了共识水平.
主要成果:
- 在大多数路径块中,达到了90%以上的共识 (5/6在第1轮,6/6在第2轮).
- 建议包括对良性瘤的观察和对恶性病理的多学科评估.
- 重点是针对中等和高风险患者的多式疗法.
结论:
- 由共识驱动的途径为腹膜间皮瘤管理提供了必要的指导,而证据有限.
- 对于临床试验招生存在一致支持.
- 进一步的研究是必要的,以产生更高质量的证据,以获得最佳的PeM治疗.
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