相关实验视频

Updated: Sep 18, 2025

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
09:53

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

Published on: February 6, 2017

11.5K

三维建模Camelus DromedariusT细胞受体马 (TRG)_三角体 (TRD) /CD1D复合体 根据TRD CDR3长度显示不同的结合相互作用

Salvatrice Ciccarese1, Marie-Paule Lefranc2, Giulia C M Perrone3

  • 1Department of Biosciences, Biotechnologies and Environment, University of Bari Aldo Moro, Via E.Orabona, 4-70125 Bari, Italy.

Antibodies (Basel, Switzerland)
|June 25, 2025
PubMed
概括

大象玛-三角形T细胞表现出多样化的T细胞受体 (TR) 结构,表明在CD1D受限制的脂质抗原呈现中发挥作用,类似于人类NKT细胞.

关键词:
3D建模是什么 3D建模是什么驼 (Camelus dromedarius) 是一只驼类的动物.IMGT 独特的编号.T细胞受体受体的 T 细胞受体.在TRG和TRD的位置上.多重序列对齐 (MSA) 是指多个序列对齐.蛋白质蛋白质相互作用

更多相关视频

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay19:05

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay

Published on: October 30, 2015

12.5K
Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain08:48

Generating De Novo Antigen-specific Human T Cell Receptors by Retroviral Transduction of Centric Hemichain

Published on: October 25, 2016

8.6K

相关概念视频

Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
818
T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
5.8K
Immunoglobulin-like Cell Adhesion Molecules01:31

Immunoglobulin-like Cell Adhesion Molecules

Immunoglobulin-like cell adhesion molecules or Ig-CAMs are a versatile group of cell surface glycoproteins belonging to the immunoglobulin protein superfamily. Ig-CAMs possess the characteristic immunoglobulin protein domains and other domains such as the fibronectin type III domain. The Ig domains are glycosylated to varying degrees in different Ig-CAMs.
Ig-CAMs exhibit either homophilic binding (to other Ig-CAMs) or heterophilic binding (to other ligands such as integrins). While most Ig-CAMs...
3.4K