评估田纳西州不适当的门诊抗生素处方中的差异
Katie A Thure1, Glodi Mutamba1, Callyn M Wren1
1Healthcare-Associated Infections and Antimicrobial Resistance, Tennessee Department of Health, Nashville, TN 37243, USA.
Antibiotics (Basel, Switzerland)
|June 25, 2025
概括
田纳西州的抗生素处方存在差异,不必要的处方不成比例地影响男性,老年人和社会脆弱地区的人. 需要有针对性的干预措施,以确保公平和适当的抗生素使用.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
背景情况:
- 在2022年,美国发布了超过2亿份门诊抗生素处方,其中30%是不必要的.
- 人口因素影响抗生素处方,但健康的社会决定因素 (SDOH) 对处方不平等的影响尚未得到充分研究.
- 这项研究调查了田纳西州门诊抗生素处方中与SDOH相关的差异.
研究的目的:
- 为了探索田纳西州抗生素处方模式中的健康不平等.
- 确定导致不必要的抗生素处方的因素.
- 评估社会脆弱性指数 (SVI) 在抗生素处方差异中的作用.
主要方法:
- 使用IQVIA LRx和Dx数据库 (2022) 与诊断相关的横截面研究.
- 抗生素处方根据适当性被分为三层.
- 多变量逻辑回归分析了年龄,性别,保险和SVI对处方的影响.
主要成果:
- 在分析的2,874,505个处方中,59.3%是不合适的 (三级).
- 女性患者和儿童接受的不适当的抗生素较少.
- 较低的SVI区域和私人保险与不适当处方的几率较低有关,而医疗补助/医疗保险受益人则有更高的几率.
结论:
- 在田纳西州的门诊抗生素处方中存在显著的健康差异.
- 男人,老年人和社会经济脆弱地区的个人更容易接受不适当的处方.
- 有针对性的公共卫生干预措施对于减少不必要的抗生素使用和解决健康不平等至关重要.
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