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Updated: Sep 18, 2025

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
12:40

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors

Published on: December 7, 2014

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骨髓纤维化:在鲁克索利提尼布失效后的治疗选择

Ruth Stuckey1, Adrián Segura Díaz1, María Teresa Gómez-Casares1,2

  • 1Hematology Department, Hospital Universitario de Gran Canaria Dr. Negrín, 35019 Las Palmas de Gran Canaria, Spain.

Current oncology (Toronto, Ont.)
|June 25, 2025
PubMed
概括

异构干细胞移植可以治愈髓纤维化,但它是有限的. 像ruxolitinib这样的JAK抑制剂可以控制症状,但不能改善存活率,这导致了对新疗法的研究.

关键词:
雅克抑制剂的使用全源性造血干细胞移植 造血干细胞移植骨髓纤维化 骨髓纤维化新的治疗方法个性化医疗是个性化的医疗.抗性/耐火性 耐火性/耐火性卢克索利提尼布 (Ruxolitinib) 是一种药物.

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