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Updated: Jul 2, 2026

High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs
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多重复合的CRISPR试验用于无放大检测miRNAs

P I Thilini De Silva1, Keshani Hiniduma1, Rachelle Canete1

  • 1Department of Chemistry, University of Connecticut, Storrs, CT 06269, USA.

Biosensors
|June 25, 2025
PubMed
概括

这项研究介绍了一种用于检测阿尔茨海默病生物标志物的新型CRISPR-Cas13a试验. 多重生物传感器实现了三种微RNA的超低检测极限,使敏感和可靠的诊断成为可能.

关键词:
阿尔茨海默病的生物标志物克里斯普尔是什么意思?克里斯普尔是什么意思?光是一种光.这就是miRNAs.多重测定多重测定

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相关概念视频

CRISPR and crRNAs02:53

CRISPR and crRNAs

Bacteria and archaea are susceptible to viral infections just like eukaryotes; therefore, they have developed a unique adaptive immune system to protect themselves. Clustered regularly interspaced short palindromic repeats and CRISPR-associated proteins (CRISPR-Cas) are present in more than 45% of known bacteria and 90% of known archaea.
The CRISPR-Cas system stores a copy of foreign DNA in the host genome and uses it to identify the foreign DNA upon reinfection. CRISPR-Cas has three different...