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Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting

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基于凝的组织工程使用HRP/H₂O₂的进展

Marino Basha¹, Ahmad Aburub¹, Filippos F Karageorgos¹

¹Department of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, School of Medicine, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.

Gels (Basel, Switzerland)

|June 25, 2025

概括

此摘要是机器生成的。

马过氧化酶 (HRP) 和过氧化 (H2O2) 能够为组织工程提供可调的凝水凝. 优化HRP/H2O2度,为各种应用优化凝特性.

关键词:

通过3D打印打印3D打印.这是一种凝凝.胡卜的过氧化酶是胡卜的过氧化酶.这是一种水凝.过氧化是一种过氧化.相互透的网络网络.微凝是一种微凝.这些纳米纤维是纳米纤维.组织工程是组织工程.伤口愈合伤口愈合

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科学领域:

生物材料科学生物材料科学
组织工程是组织工程.
聚合物化学聚合物化学

背景情况:

凝是一种具有可调节性质的生物相容聚合物,使其对组织工程有价值.
水凝制造对于组织工程应用至关重要.
胡卜过氧化酶 (HRP) /过氧化 (H2O2) 系统提供了一种有效的方法,用于创建可修改的基于凝的水凝.

研究的目的:

审查最近使用HRP/H2O2催化系统用于基于凝的水凝制造的进展.
强调HRP/H2O2在调整组织工程的凝特性中的作用.
探索新兴趋势,如在现场凝和混合生物墨水用于组织工程.

主要方法:

使用Scopus和Web of Science数据库进行了全面的文献审查.
数据提取侧重于材料,制备方法,细胞类型,动物模型和计算技术.
分析包括基于凝的同聚合物和共聚合物水凝.

主要成果:

该HRP/H2O2系统允许通过调整催化剂度来微调凝水凝的特性.
HRP和H2O2度的变化对特定组织工程需求的凝特性产生重大影响.
现场凝和混合生物墨水等新兴趋势看起来很有前途,得到细胞培养和动物模型数据的支持.

结论:

HRP/H2O2系统是一种强大的工具,用于制造用于组织工程的多功能凝水凝.
精确控制HRP/H2O2度是优化水凝性能的关键.
未来的组织工程应用可以从使用这些水凝的现场凝和混合生物墨水策略中受益.