在COVID-19后的医疗保健工作者中,光学一致性断层扫描 (OCT) 的发现
Sanela Sanja Burgić1,2, Mirko Resan3,4,5, Milka Mavija1,2
1Faculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia and Herzegovina.
光学连贯断层扫描 (OCT) 显示在SARS-CoV-2感染6个月后,中央黄斑厚度 (CMT) 增加,这表明COVID-19后的视网膜炎症. 并发症加剧了视网膜神经纤维层的稀薄,表明潜在的神经血管功能障碍.
科学领域:
- 眼科医生 眼科 眼科
- 病毒学 病毒学
- 神经科学是一个神经科学.
背景情况:
- 新出现的证据表明,SARS-CoV-2可以影响眼睛结构.
- 在COVID-19感染后,可能会发生微妙的视网膜变化.
- 先进的成像对于检测这些变化至关重要.
研究的目的:
- 通过光学连贯断层扫描 (OCT) 来研究COVID-19后的中期视网膜解剖变化.
- 为了将视网膜变化与COVID-19的严重程度和患者的并发症相关联.
主要方法:
- 追溯病例控制研究,涉及55名医疗保健工作者 (25名COVID-19,30名对照).
- 眼科检查,包括OCT成像,在感染后六个月进行.
- 对人口统计数据,并发症,疾病严重程度和治疗方法的分析.
主要成果:
- 在COVID-19后组显著增加中央黄斑厚度 (CMT) (p <0.05).
- 在CMT和COVID-19严重程度之间存在微弱的正相关性 (r = 0.245,p < 0.05).
- 视网膜神经纤维层 (RNFL) 或质细胞复合体 (GCL + IPL) 厚度没有显著差异,尽管趋势表明早期的神经退行.
- 同病患者的RNFL上/下厚度降低,表明潜在的神经血管功能损害.
结论:
- OCT对于检测COVID-19后的亚临床视网膜变化非常有价值.
- 增加的CMT表明后炎性反应.
- 建议对已康复的患者进行长期监测,特别是那些患有并发症的患者,因为可能会产生神经血管效应.
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