在患有血管合症的患者中评估胆道厚度和视网膜神经纤维层厚度
Hasan B Isleyen1, Batur G Kanar2, Guzide Akcay3
1Cardiology Department, Istanbul Nişantaşı Üniversitesi, Istanbul 34475, Turkey.
Journal of personalized medicine
|June 25, 2025
概括
与健康对照人群相比,患有血管 (VVS) 的个体表现出更厚的胆道厚度 (CT). 视网膜神经纤维层厚度 (RNFLT) 在两组之间没有差异,这表明VVS患者的胆道循环可能发生变化.
科学领域:
- 眼科医生 眼科 眼科
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 血管 (VVS) 是一种常见的疾病,其特点是暂时失去意识.
- VVS的潜在病理生理学可能涉及影响血管调节的自主神经系统功能障碍.
- 眼部微循环,包括胆道和视网膜层,可能会受到自主变化的影响.
研究的目的:
- 在患有VVS的患者中,研究胸腔厚度 (CT) 和周视网膜神经纤维层厚度 (pRNFLT).
- 为了比较VVS患者和健康对照人群之间的眼睛结构测量.
主要方法:
- 一项涉及67名VVS患者和61名健康对照者的病例控制研究.
- 扫描源光学连贯性断层扫描 (SS-OCT) 用于测量,鼻和部CT.
- pRNFLT也使用SS-OCT进行了评估.
主要成果:
- 患有VVS的患者表现出统计学上显著的厚度更高的平均叶CT (408.7 ± 92.5 μm对比342.1 ± 60.2 μm,p < 0.01).
- 鼻腔CT (385.2 ± 88.3 μm对比329.2 ± 47.6 μm,p < 0.001) 和部CT (379.5 ± 51.6 μm对比321.48 ± 43.2 μm,p < 0.03) 在VVS患者中也显著更厚.
- 在VVS患者和对照人群之间没有观察到全球或象限pRNFLT的显著差异.
结论:
- 与健康个体相比,患有血管综合症的个体在所有测量区域中都增加了胸膜厚度.
- 视网膜神经纤维层厚度在VVS患者中保持不变.
- 这些发现表明,由于局部神经递质的变化,状循环的改变可能在VVS的病理生理学中发挥作用.
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