高强度划船训练后的唾液代谢物变化和对运动诱导的肌肉损伤的潜在生物标志物查
Yue Yi1,2, Junjie Ding1,2, Baoguo Wang1,2
1School of Life Science, Beijing Institute of Technology, Beijing 100081, China.
Metabolites
|June 25, 2025
概括
唾液分析可以通过在强度炼后检测唾液代谢物显著变化来预测运动诱导的肌肉损伤 (EIMD). 这种非侵入性方法对运动员和健身爱好者肌肉健康的监测非常有希望.
科学领域:
- 运动医学 运动医学
- 生物化学 生物化学
- 运动生理学 运动生理学
背景情况:
- 运动引起的肌肉损伤 (EIMD) 是一个常见的训练风险.
- 目前的EIMD诊断依赖于血液测试或成像.
- 唾液分析为EIMD预测提供了一个有希望的,非侵入性的替代方案.
研究的目的:
- 为了研究在高强度运动后唾液代谢物的变化.
- 为了确定潜在的唾液生物标志物来预测EIMD.
- 评估唾液分析用于EIMD检测的有效性.
主要方法:
- 18名参与者接受了高强度划船训练.
- 通过血液分析和疼痛评估证实了EIMD的发生.
- 伪向的代谢学分析了运动后的唾液代谢物质变化.
主要成果:
- 观察到唾液代谢物的显著增加 (43) 和减少 (31).
- 升级的代谢物与激素分泌,抗氧化和肌肉修复相关.
- 一个预测模型确定了三种具有高灵敏度 (>88.9%) 和特异性 (>94.4%) 的唾液生物标志物,在组合代谢物中达到~100%的准确性.
结论:
- 高强度训练和EIMD显著改变了唾液代谢物概况.
- 唾液代谢物趋势反映了一些血液生化指标.
- 唾液生物标志物,特别是当它们结合在一起时,显示出对准确的EIMD预测有很大的潜力.
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