人类中的加密球菌内心炎-叙述性综述
Petros Ioannou1, Afroditi Ziogou2, Alexios Giannakodimos3
1School of Medicine, University of Crete, 71003 Heraklion, Greece.
Pathogens (Basel, Switzerland)
|June 25, 2025
概括
密码球菌内心炎是罕见的,主要影响免疫力低下的个体和心脏装置的人. 高死亡率需要在高危患者中早期识别和治疗酵母菌感染.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 菌类学 菌类学是指菌类学.
背景情况:
- 加密球菌种是机会性真菌,很少在免疫能力强的个体中引起感染.
- 加密球菌内心炎是内心脏的透,主要影响免疫力低下的患者,心脏器件或假的患者.
研究的目的:
- 综合分析已记录的人类Cryptococcus spp.病例. 心内膜炎.内心炎.心内膜炎.
- 详细介绍这种罕见感染的流行病学,微生物学,临床特征,治疗方法和结果.
主要方法:
- 进行了系统的文献审查.
- 在PubMed和Scopus数据库中搜索相关研究.
主要成果:
- 鉴定了16例加密球菌内心炎病例,平均年龄为46.6岁,81.25%的男性.
- 免疫抑制 (31.25%),末期脏病和假发门 (25%) 是常见的诱导因素.
- 主要病原体是Cryptococcus neoformans (87.5%),最频繁地影响了 mitra 和 大动脉. 死亡率很高,为56.25%.
结论:
- 这是Cryptococcus spp. 可以导致严重的全身感染,包括内心炎.
- 医疗保健提供者必须在酵母菌感染的差异诊断中考虑Cryptococcus,特别是在免疫功能低下的患者中.
- 早期诊断和适当的抗真菌治疗对于改善加密球菌内心炎的结果至关重要.
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