后COVID-19的消化表现:专注于治疗策略
Cristina Stasi1, Massimo Bellini2
1Department of Life Science, Health and Health Professions, Link Campus University, 00165 Rome, Italy.
Pathogens (Basel, Switzerland)
|June 25, 2025
概括
后COVID-19可能会导致慢性消化问题,如刺激性肠综合征,由于肠道微生物群的变化. 研究正在探索感染后这些持续的胃肠道症状的治疗方法.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 病毒学 病毒学
背景情况:
- 后COVID-19综合征表现出除了肺部表现之外的多种系统性影响.
- SARS-CoV-2 利用血管素转化酶2 (ACE-2) 受体,存在于包括消化道在内的多个器官中.
- 在COVID-19感染后肠道微生物群的变化与增加的消化系统症状有关.
研究的目的:
- 审查后COVID-19综合征的消化表现,重点关注易怒肠综合征.
- 要总结当前和新兴的治疗策略来管理这些胃肠道后果.
- 为提供最近两年内出版的最新文学概述.
主要方法:
- 以英语出版的研究的文献综述.
- 在PubMed数据库中搜索相关文章.
- 专注于过去两年的研究,涉及COVID-19后的消化问题.
主要成果:
- 观察到感染后刺激性肠综合征的发病率增加.
- 有证据表明,SARS-CoV-2在肠道组织中持续存在.
- 由病原体的多样性减少和过度生长而表现出的肠道失调是关键因素.
结论:
- 消化系统的表现,特别是易怒肠综合征,是COVID-19的显著后果.
- 针对肠道微生物群和病毒持久性的治疗策略正在调查中.
- 需要进一步的研究,以充分理解和管理长期的胃肠道并发症.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
430
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
430
Gastritis III: Clinical Manifestations and Management
500
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
500
Chronic Pancreatitis II: Collaborative Care
131
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
131
Irritable Bowel Syndrome III: Medical and Nursing Management
321
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
321
Drugs for Treatment of Diarrhea-Predominant IBS
313
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
313
Inflammatory Bowel Disease IV: Pharmacological Management
204
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
204


