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Updated: Sep 18, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
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延迟关联核抗原 (LANA) 通过抑制Nrf2/GPX4和UpregulatingMDM2促进铁

Yuejia Cao1,2, Shihan Shao1, Yingying Zhang1

  • 1School of Public Health, Hangzhou Normal University, Hangzhou 311121, China.

Pathogens (Basel, Switzerland)
|June 25, 2025
PubMed
概括

卡波西的肉瘤相关性疹病毒 (KSHV) 与潜伏相关的核抗原 (LANA) 意外地促进了ferroptosis. 拉纳抑制了谷氨过氧化酶4 (GPX4) 和核因素红色素2相关因子2 (Nrf2),导致细胞死亡增加.

关键词:
卡波西的肉瘤相关性疹病毒 (KSHV)铁性化 (ferroptosis) 是一种与延迟相关的核抗原 (LANA)鼠标双分钟2 (MDM2) 的时间.核因子红色素2相关因子2 (Nrf2)

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