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NC410是一种双价LAIR-2结构,在瘤微环境中重塑原蛋白,并取消中性粒细胞驱动的T细胞抑制

Thejaswini Giridharan1, Sora Suzuki2, Anm Nazmul H Khan3

  • 1Department of Surgery, University of Michigan, Ann Arbor, MI, United States.

Journal of immunology (Baltimore, Md. : 1950)
|June 25, 2025
PubMed
概括

卵巢癌催化液通过对LAIR-1的原结合抑制T细胞功能. 药物NC410通过向这种相互作用来恢复T细胞活性,显示出作为治疗生物标记物的潜力.

关键词:
免疫抑制是一种免疫抑制.作为一个中性粒细胞.卵巢癌是发生在卵巢中的癌症.一个T细胞细胞.瘤微环境 (TME) 是指瘤的微环境.

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