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通过基因工程和过程优化来增强Streptomyces tsukubaensis中塔克罗利斯的产量

Jiawei Zhang1, Haolong Huang1, Zhengyu Zhang2

  • 1National Key Laboratory of Lead Druggability Research, China State Institute of Pharmaceutical Industry, Shanghai Institute of Pharmaceutical Industry, 285 Gebaini Road, Pudong, Shanghai, 201203, P. R. China.

World journal of microbiology & biotechnology
|June 25, 2025
PubMed
概括

研究人员通过工程化Streptomyces tsukubaensis来增强塔克罗利斯的生产. 过度表达fkbN基因和在发酵中使用吸附剂显著提高了产量,为这种免疫抑制药物达到创纪录的水平.

关键词:
这种动物叫S. tsukubaensisensis.基因工程是一种基因工程.过程优化 过程优化塔克罗利慕斯可以使用.

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