来自29个欧洲国家的6个经常使用的抑郁症测量标准的横截面参考数据
Leili Riazy1, Mia Grote1, Gregor Liegl1
1Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Medizinische Klinik mit Schwerpunkt für Psychosomatik, Center for Patient-Centered Outcomes Research, Berlin, Germany.
JAMA network open
|June 25, 2025
概括
这项研究为欧洲抑郁症指标提供了关键的年龄,性别和国家特定的参考值. 这些发现有助于准确解释患者报告结果测量信息系统 (PROMIS) 抑郁症得分和其他常见措施.
科学领域:
- 精神病学和心理健康 精神病学和心理健康
- 流行病学 流行病学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 准确地解释抑郁症得分需要在临床和研究环境中建立横截面参考值.
- 现有的抑郁症测量需要标准化的参考点来有效评估个人和团体的表现.
研究的目的:
- 为了确定患者报告结果测量信息系统 (PROMIS) 抑郁症指标的年龄,性别和国家特定的参考值.
- 为其他六种经常使用的抑郁症指标提供参考值.
主要方法:
- 利用欧洲健康访谈调查 (EHIS) 波3 (2018-2020) 的数据,通过一般欧洲人口的患者健康问卷 (PHQ) -8评估抑郁症状.
- 采用物件响应理论 (IRT) 建模和定量回归来导出PROMIS抑郁T分数指标上的仪器独立参考数据.
- 分析了来自29个欧洲国家的287530名参与者的回答.
主要成果:
- 整个欧洲人口的PROMIS抑郁症T-score中位数为45.33,性别之间观察到差异 (男性:44.11,女性:46.37).
- 在不同欧洲国家,人们注意到抑郁症得分的显著差异,塞尔维亚的中位数得分最低 (40.81),冰岛的中位数最高 (48.60).
- 抑郁症得分显示出基于年龄,性别和居住国家的变化.
结论:
- 该研究成功生成了抑郁症指标的年龄,性别和国家特定参考值,包括PROMIS.
- 这些参考值对于对不同欧洲人口中抑郁症评估工具的准确解释至关重要.
- 该方法允许创建一个共同的,仪器独立的抑郁症评估指标.
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