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Updated: Sep 18, 2025

Feeder-free Derivation of Neural Crest Progenitor Cells from Human Pluripotent Stem Cells
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Wnt 途径诱导了原始干细胞中的原始样子子群,而 NME7AB 则导致了同质的原始样子群

Kevin R Yi1, Jac-Leen S S Nash1, Mark G Carter1

  • 1Minerva Biotechnologies, Waltham, Massachusetts, United States of America.

PloS one
|June 25, 2025
PubMed
概括

Wnt/β-catenin通路的激活可以诱导一种类似于原始的干细胞状态,增强分化潜力. 这一发现协调了有关干细胞多能性与分化的相互矛盾的报告.

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