秘鲁mpox患者的流行病学和临床特征:系统审查和元分析
Darwin A León-Figueroa1,2, Edwin Aguirre-Milachay3, Milagros Diaz-Torres1
1Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, Peru.
PloS one
|June 25, 2025
概括
莫波克斯在秘鲁不成比例地影响男性,艾滋病毒共感染率很高. 对于弱势群体,特别是艾滋病毒感染者,早期诊断和量身定制的预防策略至关重要.
科学领域:
- 流行病学 流行病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 麻疹 (以前称为麻疹) 呈现出不断演变的临床变异性,并已成为全球健康问题.
- 秘鲁在拉丁美洲的mopox病例中排名第五,需要清楚地了解当地流行病学和临床环境.
研究的目的:
- 确定秘鲁mpox患者的流行病学和临床特征.
- 提供有关秘鲁人口中mopox情况的详细观点.
主要方法:
- 对秘鲁的mopox研究进行了系统审查和元分析.
- 搜索了10个数据库,并使用Joanna Briggs Institute工具评估了研究质量.
- 随机效应元分析被用于聚合估计,在R.中进行统计分析.
主要成果:
- 包括包括3960名秘鲁mpox患者的9项研究,研究质量中等.
- 马波克斯主要影响男性 (97%),艾滋病毒共感染率高 (63%),许多人接受抗逆转录病毒治疗 (91%).
- 常见的症状包括皮肤病变 (88%),淋巴腺病 (83%),异位性皮疹 (72%),发烧 (67%) 和头痛 (52%).
结论:
- 秘鲁的Mpox在男性中患病率很高,并且与艾滋病毒共感染有显著的关联.
- 这些发现强调了这一群体的脆弱性和需要采用多学科方法,强调早期诊断.
- 建议针对弱势群体,特别是艾滋病毒感染者的预防策略和进一步的纵向研究.
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