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Updated: Sep 18, 2025

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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通过它们与核酸的相互作用,探索印尼基和基酸的抗癌性质

Tommaso Giani1, Giannantonio Tomasi1, Pablo A Nogara2

  • 1Department of Chemistry and Industrial Chemistry, University of Pisa, Via G. Moruzzi 13, 56124 Pisa, Italy.

Journal of inorganic biochemistry
|June 25, 2025
PubMed
概括

印第尼尔和基合物在槽中与核酸 (NA) 结合,而印第尼尔表现出更强的亲和力. 基合物在不同的NA结构中表现出独特的结合变异,如DNA,RNA,G-四重复和i-motif.

关键词:
在G-四重复合体中.我是一个动机.作用机制 作用机制金属药物是一种药物.核酸是核酸中的一种.帕拉复合体是一个复合体.

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