结节细胞内状层稀薄与儿科乳头发疹炎视觉功能的关联
Andrew H Malem1, Arun Y Reginald2, Michael J Wan2
1Eye institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates; Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio.
概括
儿科的乳头皮质会导致视力丧失. 在患有 papilledema 的儿童中,减少斑点结节细胞内形层厚度 (GCT) 与视力受损有关.
科学领域:
- 眼科医生 眼科 眼科
- 神经眼科神经眼科
- 儿科神经学 儿科神经学
背景情况:
- 乳头,通常是由增加的内压引起的,可以导致儿童的视力丧失.
- 斑点结节细胞内状层 (GCT) 是视网膜健康的关键指标.
- 了解GCT与儿科 papilledema视觉结果之间的关系对于早期检测和管理至关重要.
研究的目的:
- 为了研究斑点结节细胞内形层厚度 (GCT) 与被诊断为乳头炎症的儿科患者的视力损失之间的联系.
主要方法:
- 从2012年到2022年,对患有 papilledema 的儿科患者 (18岁以下) 的病历进行了回顾性审查.
- 收集的数据包括人口统计,腰部穿刺开口压力,病因,视力敏度,视网膜神经纤维层 (RNFL) 厚度和GCT.
- 视力损失和没有视力损失的患者之间的临床特征的比较.
主要成果:
- 总共分析了80名患者 (160只眼睛);14%的患者经历了视力损失.
- 患有视力损失的患者的腰部穿刺开口压力和初始RNFL厚度较高.
- 与没有视力损失的眼睛相比,在视力损失的眼睛中观察到明显减少的最终平均值和最小GCT.
结论:
- 最后的黄斑结节细胞内形层厚度 (GCT) 在患有乳头炎的儿童患者显著减少,他们经历视力损失.
- 在患有 papilledema 的儿童中,GCT 可能作为监测视觉功能的宝贵生物标志物.
相关概念视频
01:22Photoreceptors and Visual Pathways
6.5K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.5K
01:25Glaucoma: Overview
789
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
789
01:20Anatomy of the Eyeball
7.6K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
7.6K