慢性腰部疼痛与认知功能受损有关:系统性审查和元分析
Noelani Sobott1, Meagan E Crowther2, Grace E Vincent3
1Medical and Applied Sciences, Central Queensland University, Rockhampton, Queensland, Australia.
The journal of pain
|June 25, 2025
概括
与没有疼痛的人相比,患有慢性腰部疼痛 (CLBP) 的成年人在执行功能和记忆等领域表现出更差的认知功能. 需要进一步的研究来了解这些认知变化的机制和影响.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 康复医学 康复医学 康复医学
背景情况:
- 慢性腰部疼痛 (CLBP) 是一种普遍的疾病,影响全球数百万人.
- 在患有CLBP的个体中,有事报告认知功能缺陷.
- 需要进行系统性审查和元分析,以巩固现有的关于CLBP认知功能的证据.
研究的目的:
- 为了比较患有CLBP的成年人与无疼痛对照人之间的特定领域认知功能.
- 系统地审查和分析评估CLBP认知表现的研究.
- 评估关于CLBP认知功能的证据的确定性.
主要方法:
- 在PubMed,CINAHL,PsycINFO,EMBASE和CENTRAL数据库中进行了搜索.
- 使用Hedges的g进行了一对随机效应的元分析.
- 使用GRADE方法评估证据的确定性,使用JBI批判性评估检查清单评估偏差风险.
主要成果:
- 包括26项与5572名参与者的研究.
- 与对照组相比,患有CLBP的成年人在执行功能,全球认知,记忆,运动技能和处理速度方面表现明显差.
- 在注意力,语言或感知方面没有发现显著差异,尽管大多数领域的证据确定性非常低.
结论:
- 临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床临床
- CLBP可能与略差的全球认知有关,证据的确定性较低.
- 尽管缺乏关于因果机制的证据,但对患有CLBP的成年人进行认知功能评估是有必要的.
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