开发和验证个人参与者数据元分析的关键评估工具:修改的e-Delphi研究协议
Edith Ginika Otalike1, Mike Clarke2, Areti Angeliki Veroniki3,4
1Epidemiology and Biostatistics, University of Western Ontario, London, Ontario, Canada eotalike@uwo.ca.
BMJ open
|June 25, 2025
概括
本研究开发并验证了个人参与者数据元分析 (IPD-MA) 的关键评估检查清单,这是证据综合的黄金标准. 这项新工具旨在在全球范围内标准化IPD-MA研究的质量评估.
科学领域:
- *证据综合和元分析方法.
- *健康研究方法和批判性评估工具.
背景情况:
- *个人参与者数据元分析 (IPD-MA) 是证据综合的黄金标准.
- *目前的IPD-MA行为缺乏基于共识的批判性评估工具.
- * 本研究解决了对标准化IPD-MA评估检查清单的需求.
研究的目的:
- * 系统地确定IPD-MA批判性评估的质量项目.
- *为IPD-MA制定基于共识的批判性评估检查清单.
- *为了验证可靠性和内容有效性,制定了检查清单.
主要方法:
- *第一阶段:对IPD-MA指导的系统方法审查.
- *第二阶段:与国际专家和利益相关者进行e-Delphi调查,以就检查清单项目达成共识.
- *第三阶段:通过内容有效性和可靠性测试验证检查清单的有效性.
主要成果:
- *根据系统性审查,制定了初步的检查清单.
- * 通过多轮的e-Delphi调查,在检查清单项目上达成共识.
- * 检查清单经过试点测试和内容有效性和可靠性的验证.
结论:
- * 已经开发了一个IPD-MA的验证的临界评估检查清单.
- * 这种工具将提高IPD-MA的质量和标准化.
- * 检查清单将通过开放访问出版物和网络进行传播.
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