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Updated: Sep 18, 2025

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在狼中,FXR抑制功能是对致病性Tfh细胞反应的检查点阻断

Xiangyang Wang1,2,3, Linsen Ye4, Shanshan Liu2

  • 1Department of Immunology and Microbiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

Cellular & molecular immunology
|June 25, 2025
PubMed
概括

法尔内索伊德X受体 (FXR) 控制T毛囊辅助细胞 (Tfh) 扩张,对免疫反应至关重要. 抑制FXR可以通过减少自我反应性自身抗体来治疗诸如系统性红斑狼 (SLE) 等自身免疫性疾病.

关键词:
胆固醇的新陈代谢法尔内索伊德X受体 (FXR) 是一种毛囊辅助T细胞 (TFH) 是一种细胞.系统性红斑狼 (SLE) 是一种

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