炎症指标,营养状况和代谢状况与女性不孕症之间的关系
Zhenwen Zhang1, Liangyu Chen2, Huihua Chen1
1Department of Obstetrics and Gynecology, Ningde Municipal Hospital of Ningde Normal University, Ningde, China.
Reproductive health
|June 25, 2025
概括
女性不孕症与炎症,营养和代谢健康有关. 优化这些因素可能会提高生殖能力,降低生育年龄妇女不孕症的风险.
科学领域:
- 生殖健康 生殖健康
- 不孕症研究 不孕症研究
- 公共卫生 公共卫生
背景情况:
- 不孕症影响全球数以百万计的人,对女性生殖健康的影响各不相同.
- 了解这些因素对于公共卫生倡议至关重要.
研究的目的:
- 研究女性炎症指标,营养状况,代谢状况和不孕症之间的关联.
- 开发一种对不孕症风险的预测模型.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (2013-2018) 的横截面研究.
- 包括18-45岁的女性.
- 权重二进制物流回归和名ogram风险预测模型的构建.
主要成果:
- 在1250名女性中,不孕不育的发病率为12.3%.
- 确定了独立的风险因素:婚姻状况,全身免疫炎症指数 (SII),体重指数 (BMI),营养风险指数 (NRI) 和代谢综合征 (MetS).
- 一个名图模型 (AUC=0.703) 显示不孕症风险增加,而三位数得分更高.
结论:
- 炎症,营养和代谢健康与女性不孕症有显著的关联.
- 针对炎症,营养和代谢状况的干预措施可能会降低不孕症风险.
- 通过这些管理策略,可以提高生育年龄的妇女的生殖能力.
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