提高认识:巴伐利亚州高级儿科癌症息治疗的真实世界数据
Nadja Nehls1,2,3, Maja Börner1,2,3, Sebastian Ziegelmayer1
1Department of Pediatrics and Children's Cancer Research Center, TUM School of Medicine and Health, Kinderklinik München Schwabing, Technical University of Munich, Munich, Germany.
Pediatric blood & cancer
|June 26, 2025
概括
儿童瘤学中的息护理整合被显著推迟并未充分利用,即使是在高收入国家. 大多数儿童在疾病发展轨迹的晚期获得这些关键服务,错过了早期的福利.
科学领域:
- 儿科瘤学 儿科瘤学
- 抚慰性护理是一种缓解性护理.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 建议在儿科瘤学中早期整合息治疗,但往往未得到充分利用.
- 障碍往往会推迟为患有癌症的儿童提供息护理服务的实施.
- 这项研究检查了在一个高收入国家的儿科瘤学中息护理整合的现实数据.
研究的目的:
- 评估儿科瘤患者的息护理服务的利用率和时间.
- 调查影响息治疗启动和持续时间的因素.
- 分析息治疗对患者结果的影响.
主要方法:
- 在6个德国中心 (2017-2022) 进行了373名儿科瘤患者 (18岁以下) 的回顾性观察研究.
- 收集关于息护理 (发病,持续时间,频率,死亡地点),疾病特征,表现状况,治疗和生存率的数据.
- 对息治疗时间和持续时间相对于疾病轨迹和瘤类型的分析,以及基于息治疗状态的结果.
主要成果:
- 只有42% (157/373) 的患者获得了息治疗服务.
- 息治疗是晚期开始的,通常是在疾病轨迹的最后三分之一,只有16.8%的人从诊断开始.
- 患有血性恶性瘤的儿童在息护理服务中的参与率明显较低.
结论:
- 尽管有已知的好处,但息治疗在儿科瘤病患者中仍未得到充分利用和延迟.
- 在及时整合息治疗方面存在关键差距,即使在资源充足的医疗保健系统中也是如此.
- 需要进一步努力克服障碍,改善癌症儿童早期获得息治疗的机会.
相关概念视频
Cancer Survival Analysis
458
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
458
Continuing Care
1.6K
Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
1.6K
Treatment Resistant Cancers
3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K
Nursing Ethical Principles II
1.4K
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
1.4K
Cancer Therapies
8.0K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.0K
Combination Therapies and Personalized Medicine
5.1K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
5.1K


