在淋巴瘤分期过程中检测到的甲状腺附带瘤的内分泌影响,用18F-氧葡萄糖正子发射断层扫描检测
Marcos Tadashi Kakitani Toyoshima1, Roberta Morgado Ferreira Zuppani2, Isabelle Pinheiro Amaro3
1Endocrine Oncology Service, Instituto do Câncer do Estado de São Paulo Octávio Frias de Oliveira, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Clinical endocrinology
|June 26, 2025
概括
在使用FDG-PET/CT进行淋巴瘤分期期间,甲状腺附带瘤很常见. 焦点吸收表明恶性瘤的风险,需要多模式诊断方法来适当管理患者.
科学领域:
- 在瘤学瘤学.
- 核医学就是核医学.
- 内分泌学 在内分泌学.
背景情况:
- FDG-PET/CT对于淋巴瘤的分期至关重要.
- 在这些扫描中经常发现甲状腺附带瘤.
- 了解它们的含义对于患者护理至关重要.
研究的目的:
- 为了确定在淋巴瘤分期期间发现的甲状腺意外瘤的患病率和特征.
- 调查与这些偶然性瘤相关的内分泌影响和恶性瘤风险.
- 评估成像特征和临床因素在评估恶性瘤风险中的有用性.
主要方法:
- 对795名接受FDG-PET/CT的成年淋巴瘤患者进行了回顾性队列研究.
- 甲状腺吸收被分类为焦点或扩散.
- 对人口统计数据,淋巴瘤亚型,甲状腺功能,自身抗体和成像特征 (US,CT,FNAC,组织病理学) 的分析.
主要成果:
- 在17.5%的患者中检测到甲状腺异常.
- 焦点吸收 (4.2%) 的恶性瘤率为18.2%.
- 扩散吸收 (2.5%) 与自身免疫性甲状腺炎相关.
- 年龄较大和女性性别预测吸收;即使SUVmax低,恶性瘤风险也存在.
结论:
- 甲状腺附带瘤是使用FDG-PET/CT进行淋巴瘤分期的常见发现.
- 焦点吸收需要仔细评估,因为恶性瘤的风险.
- 多模式诊断策略对于最佳管理至关重要.
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