氧化低密度脂蛋白作为增强微卫星稳定结直肠癌免疫检查点抑制剂治疗的潜在目标

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Xiaochun Zhang1, Xiaorui Ye2, Heiying Jin1,2

  • 1The Second Clinical Medical College of Nanjing University of Chinese Medicine, Nanjing 210017, China.

Antioxidants (Basel, Switzerland)
|June 26, 2025
PubMed
概括

氧化低密度脂蛋白 (oxLDL) 在微卫星稳定结直肠癌 (MSS CRC) 中促进免疫检查点抑制剂 (ICI) 耐药性. 向oxLDL可能会克服这种耐药性,为MSS CRC患者提供新的治疗策略.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂免疫抑制是一种免疫抑制.代谢重编程是指代谢重编程.微卫星稳定的结直肠癌氧化应激是一种氧化应激.氧化低密度脂蛋白是一种氧化低密度脂蛋白.瘤微环境是一个微环境.

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