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Updated: May 5, 2026

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微RNA的调节性遗传网络:探索宫癌中的基因组特征

Carlos Pérez-Plasencia1, Yaneth Citlalli Orbe-Orihuela2, Armando Méndez-Herrera2

  • 1Unidad de Biomedicina, FES-Iztacala, Universidad Nacional Autónoma de Mexico, Tlalnepantla de Baz 54090, Mexico.

Biomedicines
|June 26, 2025
PubMed
概括

持续高风险的人类乳头瘤病毒 (hr-HPV) 感染通过改变microRNA和基因表达来驱动子宫癌. 识别这些基因组签名可能会导致新的精准医学治疗.

关键词:
在宫癌中通过微RNA调节遗传网络.

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相关概念视频

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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