便秘和老年抑郁症状的关联:使用JUSTICE-TOKYO前性队列研究的基线数据进行横截面分析
Hiroyuki Kiko1, Daisuke Asaoka1, Osamu Nomura1
1Department of Gastroenterology, Juntendo Tokyo Koto Geriatric Medical Center, Tokyo 136-0075, Japan.
Diagnostics (Basel, Switzerland)
|June 26, 2025
概括
经历便秘的老年人与抑郁症状有显著的关联. 这项研究强调了胃肠道问题与老年人精神健康之间的联系.
科学领域:
- 老年学是一门学科.
- 精神病学是一个精神病学.
- 胃肠病学 胃肠病学
背景情况:
- 在老年人群中,抑郁症状是一个很大的问题.
- 胃肠道疾病,包括便秘,在老年人中很普遍.
- 身体健康状况与老年人的心理健康之间的关系需要进一步研究.
研究的目的:
- 调查老年人队伍中便秘和抑郁症状之间的相关性.
- 确定与老年人抑郁症状相关的潜在风险因素.
主要方法:
- 一项采用JUSTICE-TOKYO队列的基线数据进行的横截面研究.
- 参与者 (n=984) 进行了评估,包括老年抑郁量表15 (GDS-15),迷你精神状态检查 (MMSE) 和便秘评分系统 (CSS).
- 进行了相关性和多重回归分析,以评估GDS-15分数与各种健康参数之间的关联.
主要成果:
- 老年抑郁症状 (GDS-15分数) 与体重指数 (BMI),MMSE和各种生活质量 (QOL) 措施有显著的相关性.
- 具体来说,较高的GDS-15分数与较差的便秘相关的QOL和较高的CSS分数有关.
- 多重回归分析证实了GDS-15得分与BMI,MMSE,便秘相关的QOL,反射相关的QOL,腹相关的QOL和CSS之间的显著关联.
结论:
- 老年人的抑郁症状与多种腹部症状有关,便秘显示出明显的联系.
- 这项研究表明,老年人中便秘和抑郁症状之间存在显著的关系.
- 横截面设计排除了抑郁症状和便秘之间的因果推断.
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