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Updated: Sep 18, 2025

Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish
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尿素是一种治疗性核酸盐,通过SRC激酶激活加剧酒精性肝病:一个网络毒理学和分子动力学的视角

Zhenyu Liu1, Zhihao Wang1, Jie Wang1

  • 1Organ Transplantation Institute of Xiamen University, Xiamen Human Organ Transplantation Quality Control Center, Xiamen Key Laboratory of Regeneration Medicine, Fujian Provincial Key Laboratory of Organ and Tissue Regeneration, School of Medicine, Xiamen University, Xiamen 361102, China.

International journal of molecular sciences
|June 26, 2025
PubMed
概括

尿素是一种血液代谢物,通过与关键细胞标相互作用,可能会使酒精性肝病 (ALD) 恶化. 这项研究揭示了ALD治疗的潜在新治疗策略.

关键词:
酒精性肝病是一种肝病.门德尔的随机化是门德尔的随机化分子动力学模拟模拟网络毒理学网络毒理学一个单细胞RNA测序.

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The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
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