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在Xenopus laevis中的海绵bHLH基因表达扰乱了内耳和侧线神经感官发育和视觉异位路径

Karen L Elliott1, Clayton Gordy1, Hannah Ingvalson1

  • 1Department of Biology, University of Iowa, Iowa City, IA 52245, USA.

International journal of molecular sciences
|June 26, 2025
PubMed
概括

在青胚胎中过度表达海绵基因AmqbHLH1会破坏内耳和侧线发育,导致这些神经感官器官的剂量依赖性损失. 这表明AmqbHLH1具有抗神经传感效应,单基因过度表达可能无法确保稳定的细胞命运变化.

关键词:
神经节点1是一个神经节点.亚特纳尔的第一个.这就是为什么BHLHH内耳的内耳,就是内耳的内耳.侧面线的侧面线是神经感官发育的发展.

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